I have downloaded and am in the process of preparing 3,370 compounds that inhibit TB (whole organism assays) with an MIC (minimal inhibitory concentration) < 1 microMolar for docking against 2,580 models of TB proteins (65% of the proteome) created by Sir Tom Blundell's group in Cambridge. This will create ~87m docking calculations that will need to be done by the BOINC server to try to find the target protein for each of these compounds.
We should have this ready by mid Jan 2014.
I hope you'll all stay with us until then.
Have a fabulous Christmas holiday.
ps: Initially we'll use the FM@H server until we have a new FTB@H server in place.
18 Dec 2013, 11:11:03 UTC
Errors in current batch or WUs - BACK ONLINE
I'm sure you have noticed errors in the latest batch of WUs. This is due to formatting errors on a few ligands and results in many failed WUs because each ligand is paired with each receptor, therefore 1 failed ligand is muliplied by the number of proteins with which it is docked.
We have always had some errors in our ligands but the rate has been quite low (< 0.5%) overall until now. As the rate has increased (8% in the last 24 hours), I will be disabling the work generator until tomorrow afternoon while I weed out some of the errors.
Thanks for the feedback,
18 Nov 2013, 18:46:47 UTC
We had a power outage over the weekend. The server is back up now and we should be up and running with new WUs in the next 30 mins.
11 Nov 2013, 11:02:54 UTC
No new tasks for 24 hours
Sorry guys but the server is overloaded at the moment. We have stopped submitting new tasks while the daemons catch up. Also, we are going to start a new experiment tomorrow afternoon. Hopefully we will be up and running by 5.
4 Nov 2013, 17:57:50 UTC
Brief interruption to supply of tasks
We are preparing the next experiment now. We expect to have more tasks this evening.
1 Nov 2013, 10:16:01 UTC
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